Fig 5.tif (1.11 MB)
The positive correlations between the levels of the plasma LDL-C and Aβ in the hippocampus of APPswe/PS1dE9 mice were presented in the scatter diagrams.
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posted on 2017-03-30, 18:08 authored by Li Shen, Bing Han, Yuan Geng, Jinhua Wang, Zhengmin Wang, Mingwei WangThe positive correlation between the levels of plasma LDL-C and the Aβ42 in the hippocampus of 7-month-old APPswe/PS1dE9 mice was illustrated in Fig 5A (r = 0.875); the positive correlation between the levels of plasma LDL-C and Aβ40 in the hippocampus of 7-month-old APPswe/PS1dE9 mice was illustrated in Fig 5B (r = 0.728). Vehicle-treated APPswe/PS1dE9 transgenic group, red; 30 mg/kg TSA-treated group, green; 60 mg/kg TSA-treated group, purple.
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WT3.5 monthsmetabolites alterationGC-TOF-MSAPPsweLDL-C levelvitamin metaboliteshippocampuConclusions TSAacquisition phasePICHOL levelNOR7 monthsvitamin metabolismmemory impairment14 weeksplasma levelmemory impairmentsELISApreference indexTSA-treated groupFBGGOPODsalvia miltiorrhizasalvianolic acidplasma lipid levelsMWMstep-through tasksglucose -6-phosphate sucrose -6-phosphatecolor methodssalvianolic acid Purposecarbohydrate metabolism
