ppat.1010400.s001.tif (125.46 kB)
The graph shows the percentage of CD69+ and CD69- cells after FACS sorting of primary B cells treated for 24 hours with a stimulatory cocktail containing 20 ng/mL Interleukin 4 (IL-4), 5uM CD40 ligand (CD40L), and 25 ng/mL CpG oligodeoxynucleotides.
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posted on 2022-04-14, 17:25 authored by Lisa Beatrice Caruso, Rui Guo, Kelsey Keith, Jozef Madzo, Davide Maestri, Sarah Boyle, Jason Wasserman, Andrew Kossenkov, Benjamin E. Gewurz, Italo Tempera(TIF)
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infects almost 95epstein barr virusebv lytic reactivationviral dna entryseveral cellular factorsessential epigenetic regulatorlatently infected cellsregulate chromatin compositionnuclear lamina bindsebv latent infectionebv infection affectsebv genome persistsebv episome contributescontrolling ebv latencylatency types correlateviral gene expressionnuclear laminaebv genomeebv episomeviral genomelatency typesviral genesseveral malignanciesepigenetic controlchromatinized episomecells expressingb cellsxlink ">varying stagesvarious malignanciesusing chiptypically asymptomaticrestrictive functionpreviously demonstratedpopulation worldwidelymphoid originlimited setimmunocompromised individualshost responsedifferent patternsdata indicatebinding correlates
