The frequency of nt variations versus nucleotide position in the gRNA.
figureposted on 2016-07-11, 16:12 authored by Laura E. Kirby, Yanni Sun, David Judah, Scooter Nowak, Donna Koslowsky
Gray bars indicate the number of gRNA sequence classes with an identified nt difference between related procyclic and bloodstream gRNAs. Nucleotide numbering for each gRNA was normalized by setting the start of the Watson-Crick anchor region to zero. Black bars indicate the number of gRNA sequence classes whose contiguous Watson-Crick anchors end at that position (start of Watson-Crick = zero, so this is an indication of the length of the contiguous Watson-Crick region).
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mitochondrial mRNA transcriptsguide RNAsRNA editingWatson-Crick anchor regionmRNA sequencesNucleotide variationsgRNA populationsTrypanosoma bruceibloodstream gRNAgene expressionlife cycle stagesEATRO 164 cell lineediting patternsgRNA transcriptomenucleotide variationstranslatable mRNAsbloodstream formmitochondrial genomeinsect stage gRNA transcriptomelife cycle transcriptomes showRNA editing processTrypanosoma brucei EATRO 164 Bloodstream Guide RNA Transcriptome