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The expression of osteogenic and chondrogenic genes in VB-BM versus IC-BM MSCs.

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posted on 24.05.2018, 18:01 authored by Evangelos M. Fragkakis, Jehan Jomaa El-Jawhari, Robert A. Dunsmuir, Peter A. Millner, Abhay S. Rao, Karen T. Henshaw, Ippokratis Pountos, Elena Jones, Peter V. Giannoudis

A. The gene expression levels during the osteogenic differentiation of VB-BM and IC-BM MSCs (4 donor-matched pairs) were assessed using TaqMan real time PCR. The gene expressions of samples collected at 1, 2 and 3 weeks of osteogenesis were calculated relative to undifferentiated cells. B. The gene expression levels during the chondrogenic differentiation of VB-BM and IC-BM MSCs (4 donor-matched pairs) were assessed using TaqMan real time PCR. The gene expressions of samples collected at 1, 2 and 3 weeks of chondrogenesis were calculated relative to undifferentiated cells. *: p<0.05. Dotted lines indicate the basal expression level of genes in undifferentiated cells.

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