pntd.0011520.g001.tif (1.78 MB)
Download fileThe effects of E. multilocularis infection on hepatic fibrosis in mouse.
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posted on 2023-07-25, 17:38 authored by Shanling Cao, Dexian Wang, Yixuan Wu, Junmei Zhang, Lixia Pu, Xuenong Luo, Xueyong Zhang, Xiaolin Sun, Yadong Zheng, Shuai Wang, Xiaola Guo(A) Representative pictures of Hematoxylin and Eosin (H&E), Masson’s Trichrome, and Picrosirius Red staining for liver fibrogenesis in control mice, high-fat diet induced mice, and E. multilocularis-infected mice. Arrows indicate cysts. (B) The birefringent collagen content was quantified in Masson’s Trichrome- or Picrosirius Red-stained sections by color thresholding-based segmentation using ImageJ.
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hepatic stellate cellsdiv >< pcol1 &# 945>- infected mice3 ’ utrhepatic fibrosis inducedechinococcus multilocularis activated hscs couldmultilocularis liver fibrosisactivated hscszbtb7a vitro gfap e 1 β signalingsuppressed zbtb7anovel strategynegatively correlatedmolecular mechanismmediated tgfkey regulatorkey eventhistopathological charactersdominantly expressed
