The alignment of genomic DNAs of Mir125b2 KO mouse lines.
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posted on 2024-07-08, 18:46 authored by Tomohiro Ogasawara, Shota Ito, Shintaro Ogashira, Tomonori Hoshino, Yusuke Sotomaru, Yuji Yoshiko, Kotaro TanimotoThe top line indicates a wild-type mouse sequence (UCSC Genome Browser, https://genome.ucsc.edu/) as a reference, and the others are sequences from F0 mice in Line 1−Line 9. The sequences of the Mir125b2 precursor, PAM, and gRNA are enclosed within the frame.
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multiple cellular processesgrew normally withoutdiv >< pattracting greater attention>- deficient micemature mir125b transcriptsmir125b expression profilesmir125b transcriptsexpression profilesvarious organsresults indicatenecessarily correlateincluding osteoblastogenesisgenetic ablationfuture studiesexpression patternsdifferentially expressedconditional deletionbone phenotypesbone parametersapparently involved); however
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