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TR4 and TR9 support effects of Sorafenib on human hepatoma cell viability.

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posted on 2016-08-12, 17:32 authored by Nicole Lange, Armelle Tsamo Tontsa, Claudia Wegscheid, Pierre Mkounga, Augustin Ephrem Nkengfack, Christine Loscher, Gabriele Sass, Gisa Tiegs

HepG2 cells were incubated with 2 μM TR3, TR4 or 1 μM TR9 either alone or in combination with Sorafenib (A, 5 μM; B, 7.5 μM) for 24 hours. Cell viability was measured by MTT assay. ★★ p ≤ 0.01; ★★★ p ≤ 0.001.

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    Rubescin E Induce Apoptosishepatoma cell lines HepG 2havanensin type limonoids10 μ MTR 9TR 4hepatoma cell viabilityplant Trichilia rubescens Olivhistone deacetylase inhibitor SAHALimonoids TS 3NFsupport Sorafenib effectssupport future HCC therapyHuman Hepatoma Cell LinesTC 50slimonoids TR 4TR 9 exhibit

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