Supplementary Materials（FigureS1-S8）

Figure S1: The number of lipid molecules in plasma was counted.Figure S2: Bar graph with standard error of the proportion (%) of the total kurtosis of the lipid subclasses in plasma. The X-axis is the subclass of lipids, the Y-axis is the proportion (%) of the total kurtosis, and the bar graph represents the Mean+SE of the sample group.Figure S3:Comparative analysis of the relative content of lipid group subclasses in the plasma. (A) Relative abundance of significantly up-regulated lipid group subclasses. (B) Relative abundance of significantly down-regulated lipid group subclasses. (Significance is shown using Welch’s t-test, with the specific p-value noted in the graph and also denoted by asterisks (*, p < 0.05, **, p < 0.01, ***, p < 0.001, ****, p < 0.0001); ns, no significance (p > 0.05).Figure S4:Volcano diagram of plasma differential lipid molecules.Figure S5: Statistics of differential lipid molecules.Figure S6: Hierarchical clustering plot of significantly different lipids of plasma.Figure S7a: Heat map of correlation coefficient matrix for Top300 significantly different lipid molecules.Figure S7b: Heat map of correlation coefficient matrix for Top10 significantly different lipid molecules.Figure S8: Bar graph of KEGG pathway enrichment.