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HVCF Treatment with exosomes isolated from hCBSCs does not significantly alter baseline transcriptional profile. Differential expression of NHCFs treated with hCBSC exosomes as compared to untreated NHCFs. A) PCA plot of NHCF-VEH compared to VNHF-EXO showing significant overlap withing the groups. B) Volcano plot analysis showing only 1 transcript with a FC >=|1.5| and FDR<=0.05.