figshareBrowse
Fig 1.tif (268.66 kB)
Download file

Structure of fosmetpantotenate.

Download (268.66 kB)
figure
posted on 09.03.2018, 18:40 authored by Daniel Elbaum, Maria G. Beconi, Edith Monteagudo, Annalise Di Marco, Maria S. Quinton, Kathryn A. Lyons, Andrew Vaino, Steven Harper

Structure of fosmetpantotenate.

History

Usage metrics

Read the peer-reviewed publication

Fosmetpantotenate (RE-024), a phosphopantothenate replacement therapy for pantothenate kinase-associated neurodegeneration: Mechanism of action and efficacy in nonclinical models
PLOS ONEPLOS ONE

Categories

Keywords

pantothenate kinase 2-REphosphopantothenic acidshort-hairpin RNA pantothenate kinase 2 gene-silenced neuroblastoma cellspantothenate kinase-associated neurodegenerationblood-brain barrier modelphosphopantothenic acid prodrugisotopically labeled-fosmetpantotenatephosphopantothenate replacement therapy10- day dosingbrain coenzymeFosmetpantotenatepantothenate kinase enzymes

Licence

CC BY 4.0

Exports