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Stereorenderings of the LTR 3′ end processing sequences found in the different structures

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posted on 31.12.2011, 02:55 by Sherwin P. Montaño, Marie L. Coté, Monica J. Roth, Millie M. Georgiadis

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Taken from "Crystal structures of oligonucleotides including the integrase processing site of the Moloney murine leukemia virus"

Nucleic Acids Research 2006;34(19):5353-5360.

Published online 26 Sep 2006

PMCID:PMC1636480.

© 2006 The Author(s)

The structures of () the first 5 bp of LTR-B1 (blue) and LTR-B2 (red) are superimposed highlighting the regions of conformational variation within this structure, () d(TTTCATT) from LTR-A (orange) and LTR-B (blue and red); () d(TCAT) from all four structures are superimposed. () The superimposed structures of d(TCAT) from the MMLV LTR-A structure (shown in orange) and d(GCAG) from one of the nine best calculated HIV-1 U5 LTR NMR structures (shown in light blue). The structures shown are the MMLV LTR and HIV-1 U5 LTR with the most similar roll angles for the CA dinucleotide.

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