Stereorenderings of the LTR 3′ end processing sequences found in the different structures
Taken from "Crystal structures of oligonucleotides including the integrase processing site of the Moloney murine leukemia virus"
Nucleic Acids Research 2006;34(19):5353-5360.
Published online 26 Sep 2006
© 2006 The Author(s)The structures of () the first 5 bp of LTR-B1 (blue) and LTR-B2 (red) are superimposed highlighting the regions of conformational variation within this structure, () d(TTTCATT) from LTR-A (orange) and LTR-B (blue and red); () d(TCAT) from all four structures are superimposed. () The superimposed structures of d(TCAT) from the MMLV LTR-A structure (shown in orange) and d(GCAG) from one of the nine best calculated HIV-1 U5 LTR NMR structures (shown in light blue). The structures shown are the MMLV LTR and HIV-1 U5 LTR with the most similar roll angles for the CA dinucleotide.