Fig 2.tif (373 kB)
Spearman correlations between percentages of CD8+CD38+HLA-DR+ T-cells and IFN-α gene expression measurements, HLA-A*0201 positive patients (n = 57).
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posted on 2017-01-03, 19:25 authored by Marie-Quitterie Picat, Isabelle Pellegrin, Juliette Bitard, Linda Wittkop, Cécile Proust-Lima, Benoît Liquet, Jean-François Moreau, Fabrice Bonnet, Patrick Blanco, Rodolphe ThiébautACTHIV study. A) ADAR: r = 0.31, p-value = 0.0180; B) ISG15: r = 0.34, p-value = 0.0085; C) IFIT1: r = 0.32, p-value = 0.0166; D) Mx1: r = 0.29, p-value = 0.0301; E) OAS1: r = 0.35, p-value = 0.0077.
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design Cross-sectional studyHIV -1-infected patientsOASalpha-interferon pathwayautoimmune-induced responseHLA-DRHLA-A 2-restricted testsIFNpp -65 ELISPOTcytomegalovirus-induced responseIFITISGANRS CO 3 Aquitaine CohortSEMExplore Chronic Immune T-Cell ActivationSuccessfully Treated HIV Patients ObjectivesCIAHIV-infected patients5 alpha-interferon-stimulated genes ADAR
