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Sometimes stable things are exciting because they don't get excited

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posted on 2025-05-09, 10:32 authored by Matthew PartridgeMatthew Partridge

Single-panel cartoon: one chemist proudly shows a bench-stable amidine-based azanide surrogate while another pokes it, surprised that “it’s not doing anything.” The creator confirms its inertness, highlighting the surrogate’s stability for safe nucleophilic amination of aryl halides. Humorous dialogue underscores practical advantages of handling a normally reactive –NH₂ equivalent.

This cartoon abstract was prepared for the RSCPoster 2025 submission Nucleophilic Amination of Aryl Halides with an Azanide (–NH₂) Surrogate by Bradley Cooper.

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Two scientists with a bench-stable azanide surrogate; one pokes it while the other proudly notes its inertness

Transcript

Person 1: Look at this. I’ve made a bench-stable amidine-based azanide surrogate. Person 2: Ooo… It’s not doing anything? Person 1: Exactly! Person 2: Cool

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