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Download fileSex differences in survival after STm infection.
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posted on 2022-04-13, 17:51 authored by Kristin Scoggin, Rachel Lynch, Jyotsana Gupta, Aravindh Nagarajan, Maxwell Sheffield, Ahmed Elsaadi, Christopher Bowden, Manuchehr Aminian, Amy Peterson, L. Garry Adams, Michael Kirby, David W. Threadgill, Helene L. Andrews-PolymenisA. Survival time and B. percent weight change after infection with STm. Strains are in ascending order of survival and weight change if survival was equal between strains. Bacterial burden in C. liver and D. spleen. Dots represent individual mice; black dots represent males and grey dots represent females. Solid lines represent medians for strain and sex. A two-tailed Student’s T test was used to determine statistical significance (* P <0.05).
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weakly negatively correlatedcomplete blood countsidentified loci associateddaily active periodinfection baseline temperaturescause disseminated diseasesalmonella enterica stm infection acrossseveral cc strainschr 1 intervaldisseminated diseasesalmonella less activedisease progressionstm infectionsusceptible strainssurviving strainsslc11a1 ses2 ncf2 mouse strainscc strainstissue damagestm ),spread systemicallysex differencesseven daysserum cytokinesmaking temperaturelower prelimiting gastroenteritishost geneticshighly colonizeddetected earlierdata revealeddata revealcollaborative crosscbc ),better detectoractivity disruptions>, known4 associated
