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Scheme of the systems investigated in this work.

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posted on 2017-09-28, 18:10 authored by David C. Malaspina, Gabriel Longo, Igal Szleifer

a) Antibody conjugated nanoparticle with antibodies covalently bonded to the nanoparticle. b) Antibody conjugated nanoparticle with antibodies bonded through streptavidin-biotin. *) Scheme of the coarse grain model of the antibody b12 (cyan) having a 50 units spacer and an antigen gp120 bound (blue).

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Behavior of ligand binding assays with crowded surfaces: Molecular model of antigen capture by antibody-conjugated nanoparticles
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antibody-conjugated nanoparticles Ligand-receptor bindingLigand binding assayssurface coverageligand-receptor binding equilibriumligand binding assaysAcNPLBAbinding behavior

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