Schematics of H2O2 (A) and OSCN- (B) production assays.
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posted on 2024-08-14, 17:31 authored by Maïwenn Petithomme-Nanrocki, Nathan Nicolau-Guillaumet, Nicolas Borie, Arnaud Haudrechy, Jean-Hugues Renault, Sophie Moussalih, Anaëlle Muggeo, Thomas GuillardSchematics of H2O2 (A) and OSCN- (B) production assays.
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reactive oxygen speciesassessing whether pathogensoxidative stress independentlyantibacterial oxidative responsehuman airway epitheliumdiv >< pconcentrations produced withinsup >-7 5 4 2 thirteen clinical strainsbacteria upon exposureantibiotic resistance phenotypestaphylococcus aureus pseudomonas aeruginosa hae oxidative responseclinical strainsp aureus aeruginosa oxidative responsessteadily producedairway secretionsvitro throughput screeningstarting pointshowed resistanceroughly 50results demonstratedpreliminary testsperformed mainlymolecules targetingml inoculamajor linehydrogen peroxidehour postfully characterizedforming unitdefense protectingcould servecomprehensively characterized15 minutes
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