Schematic diagram of the enzymatic hydrolysis of the amygdalin-nitrile group to its amides and carboxylic acid

article - DOI: 10.2174/1871520620666200313163801
monograph - DOI: 10.5281/zenodo.7295357 | ISBN: 978-619-91534-4-4
ATLAS - presentation of the finale information in the most applied and convenient form of application - DOI: 10.5281/zenodo.8009390 | ISBN: 978-619-91534-5-1

...In addition to cobalt ions, the catalyst may also be cobalt linked to a covalent bond. For example, Nitrile Hydratases (NHases; EC 4.2.1.84). They are metal-containing enzymes that convert the nitrile and / or cyano group to amides, including the Amygdalin.

The optimum action of nitrile hydratase, for example from Rhodococcus rhodochrous, is from 5.5 to 8.5 pH. Their activity is highest in the range of 10-80 degrees, and their effect is from 20 minutes to 8 hours. The acidity in the stomach is much higher and from there these enzymes will be inhibited and even agglutinated.

The peoples studied have consumed large quantities of apricot and other fruit oils. Much of the prokaryotes and eukaryotes that produce nitrile hydratases live in lakes or in the moist environment around them. There is a possibility, due to technological processes, to enter and live for a long time in these oils. Thus, these insecurities may have lived in unprotected vessels and catalytically hydrolyze the Amygdalin nitrile group to amide and / or carboxylic acid...