Schematic diagram of the enzymatic hydrolysis of the amygdalin-nitrile group to its amides and carboxylic acid

<p><b>article</b> - <b>DOI:</b> <a href="http://dx.doi.org/10.2174/1871520620666200313163801" rel="noreferrer" target="_blank">10.2174/1871520620666200313163801</a><br><b>monograph</b> - <b>DOI:</b> <a href="https://doi.org/10.5281/zenodo.7295357" rel="noreferrer" target="_blank">10.5281/zenodo.7295357</a> | ISBN: 978-619-91534-4-4<br><b>ATLAS</b><b> </b>- presentation of the finale information in the most applied and convenient form of application - <b>DOI:</b> <a href="https://doi.org/10.5281/zenodo.8009390" rel="noreferrer" target="_blank">10.5281/zenodo.8009390</a> | ISBN: 978-619-91534-5-1</p><p>...In addition to cobalt ions, the catalyst may also be cobalt linked to a covalent bond. For example, <i>N</i><i>itrile Hydratases</i> (<i>NHases; EC 4.2.1.84</i>). They are metal-containing enzymes that convert the nitrile and / or cyano group to amides, including the <i>Amygdalin</i>.</p><p>The optimum action of <i>nitrile hydratase</i>, for example from <i>Rhodococcus rhodochrous</i>, is from 5.5 to 8.5 pH. Their activity is highest in the range of 10-80 degrees, and their effect is from 20 minutes to 8 hours. The acidity in the stomach is much higher and from there these enzymes will be inhibited and even agglutinated.</p><p>The peoples studied have consumed large quantities of apricot and other fruit oils. Much of the prokaryotes and eukaryotes that produce <i>nitrile hydratases</i> live in lakes or in the moist environment around them. There is a possibility, due to technological processes, to enter and live for a long time in these oils. Thus, these insecurities may have lived in unprotected vessels and catalytically hydrolyze the <i>Amygdalin</i> nitrile group to amide and / or carboxylic acid...</p>