Sample results of vessel detection in UWFFA images using our automated algorithm show that the algorithm is able to detect vessels that are difficult to identify manually in low-contrast images.

From left to right: original ultra-widefield fluorescein angiography (UWFFA) image, enlarged views of rectangular regions that have low contrast, and the corresponding automatically detected vessel maps, and contrast-enhanced views. Our automated detection algorithm detects fine vessels that are difficult to manually identify in low contrast views and are verified as actual vessels by the contrast enhanced views.