Safranin-O/fast green staining of plug cartilage and the shaved area (original magnification 10×)

Copyright information:

Taken from "Acoustic stiffness and change in plug cartilage over time after autologous osteochondral grafting: correlation between ultrasound signal intensity and histological score in a rabbit model"

Arthritis Research & Therapy 2004;6(6):R492-R504.

Published online 14 Sep 2004

PMCID:PMC1064862.

Copyright © 2004 Kuroki et al.; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.

No abnormalities were observed at day 0. The plug (between the arrows) was inserted flush with the surrounding articular surface and the site of the shaved area (between the triangles) was clearly recognizable. There was a space between the plug and the surrounding tissue. At 2 weeks postoperatively, the plug (between the arrows) had subsided a little and newly formed tissue covered half of the plug. No tissue was observed at the site of the shaved area (between the triangles). There was a slight space between the plug and the surrounding tissue. The implanted osteochondral plug (between the arrows) had united in the subchondral bone area by 4 weeks postoperatively. The newly formed reparative tissue, which stained faintly with safranin-O, covered the plug cartilage and the plug cartilage was well stained. No tissue was observed at the site of the shaved area (between the triangles). Bony union was observed between the plug and the host.