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Download fileSIMCoV model components and their interactions.
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posted on 2021-12-23, 18:52 authored by Melanie E. Moses, Steven Hofmeyr, Judy L. Cannon, Akil Andrews, Rebekah Gridley, Monica Hinga, Kirtus Leyba, Abigail Pribisova, Vanessa Surjadidjaja, Humayra Tasnim, Stephanie ForrestEpithelial and T cells are represented as agents; virions and inflammatory signals are represented as concentrations. Numbered transitions are described in Materials and Methods.
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virus spreads fasterundifferentiated 3d gridspatially dispersed infectionsbranching airway structureaffect viral persistencescalable computational modelincreased viral loadsincorporating spatial interactionsmodel also showscell immune responsecomputational modelviral loadsimmune responsecell responseviral spreadxlink ">temporal dynamicssimulates hundredssimcov providessimcov ),results illustrateparsimonious explanationkey questioninitial sitesimprove understandinghost dynamicsexplicitly represented2d layer
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