pgen.1010535.s002.tif (774.33 kB)
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posted on 2022-12-12, 18:36 authored by Lavisha Parab, Sampriti Pal, Riddhiman DharDistribution of expression noise of genes at the mRNA level (A) and at the protein level (B).
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specific transcription factorregulating transcription factorspoor predictive powerintegrated statistical modelxlink "> noisetata box sequencespecific molecular featurespromoter nucleosome occupancytf binding sitesregulatory tfs meantcooperatively binding tfsgene expression noisetata boxtf bindingregulatory tfspredict noisenoise regulationwork uncoverstherapy resistancestochastic simulationsrelative importanceprimary driverphenotypic heterogeneitymutation penetrancekey predictorimportant implicationsgenerates heterogeneitygene regulationcellular phenotypescellular pathwayscancer growthantibiotic persistence
