Representative images of S. aureus biofilm grown on CDC Biofilm Reactor® coupons and 4 mm diameter glass beads.
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posted on 2025-02-10, 18:38 authored by Annika L. Gilmore, Helena Vu, Travis Martinez, Lousili Peniata, Brooke Kawaguchi, David A. Armbruster, Nicholas N. Ashton, Dustin L. Williams(A) 500x image of biofilm on a coupon. (B, C) at 1000x, coupon biofilm exhibited thick, multilayered plumes. (D) 500x image of bead biofilm. (E, F) 1000x images of bead biofilm also displayed multiple plumes that appeared slightly less dense than biofilm grown on coupons.
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work offered insightsimulate bacterial growthdiverse environmental conditionssignificantly greater reductionpreclinical models ).throughput biofilm growthdiv >< pbioburden per mmstaphylococcus aureus pseudomonas aeruginosa glass beads compared2 laboratory grown biofilmsaureus aeruginosa significant reductionvivo vitro p 035 ).014 ).translation acrosssurface areasupport developmentsmaller differencesresults indicatedprovide highglass beadbiofilms grownbiofilm therapiesbeads wouldantibiotic screeningantibiotic responseantibiofilm efficacy
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