pone.0212076.g007.tif (1.04 MB)

Representative examples of reperfusion events in cells subjected to 5 mM Ni2+.

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posted on 2019-02-07, 19:02 authored by Katie J. Sciuto, Steven W. Deng, Alonso Moreno, Alexey V. Zaitsev

All labeling and notations are the same as in Figure, unless indicated otherwise. Note overall blunted dynamics of Fluor-4 signal during reperfusion, including the case when no apparent [Ca2+]Cy overload ever occurred (B). Arrow in C indicate the time when TO-PRO3 was added to perfusate, immediately revealing that the sarcolemmal permeabilization had already occurred.