ppat.1010322.s004.tif (3.26 MB)

Reovirus infectivity is reduced in KO cells infected with virions but not ISVPs.

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posted on 2022-03-09, 18:30 authored by Paula Ortega-Gonzalez, Gwen Taylor, Rohit K. Jangra, Raquel Tenorio, Isabel Fernandez de Castro, Bernardo A. Mainou, Robert C. Orchard, Craig B. Wilen, Pamela H. Brigleb, Jorna Sojati, Kartik Chandran, Martin Sachse, Cristina Risco, Terence S. Dermody

WT, KO, and KO+ HBMECs were adsorbed with reovirus (A) virions or (B) ISVPs at MOIs of 10,000 or 100 particles/cell, respectively, fixed at 18 h post-adsorption, and stained for reovirus antigen using IF. Representative micrographs are shown.