Relative affinity of 1F5 and 6E2 mAbs for the denatured monomeric and the native hexameric ZNS1 conformations.

Standard curves of denatured monomeric or native hexameric HEK293-expressed ZNS1 detected by iELISA with (A) 1F5 or (B) 6E2 mAbs. Each point of the curve represents mean±SEM of three sample replicates. IC50 values of the mAbs are indicated.