pone.0211108.g002.tif (201.38 kB)

Relationship of methylation abnormality of the CDO1 gene in small bowel cancer tissue with clinicopathological features.

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posted on 24.01.2019 by Keita Kojima, Takatoshi Nakamura, Yosuke Ooizumi, Kazuharu Igarashi, Toshimichi Tanaka, Keigo Yokoi, Satoru Ishii, Nobuyuki Nishizawa, Hiroshi Katoh, Yoshimasa Kosaka, Takeo Sato, Masahiko Watanabe, Keishi Yamashita

A: Result of a t-test on tumor diameter (cutoff value = 3.5 cm). Significantly high methylation was observed in the group with a tumor diameter that was larger than 3.5 cm. B: Relationship between tumor diameter and the CDO1 TaqMeth V. As the tumor diameter increased, methylation was high. C: Comparison of the TaqMeth V in each stage. There was a significant difference between non-cancerous mucosa and pStage I. But, there was no significant difference in the TaqMeth V between stages. High methylation was found from Stage I.

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