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Relationship between Kellgren–Lawrence grading (KL), joint space width (JSW) and biochemical markers

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posted on 31.12.2011, 04:37 by Masaaki Takahashi, Kenichi Naito, Masashi Abe, Tomokazu Sawada, Akira Nagano

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Taken from "Relationship between radiographic grading of osteoarthritis and the biochemical markers for arthritis in knee osteoarthritis"

Arthritis Research & Therapy 2004;6(3):R208-R212.

Published online 12 Mar 2004


Copyright © 2004 Takahashi et al., licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.

Pyridinoline (Pyr) level is expressed as nmol/mmol creatinine. There were significant relationships between joint space width (= 0.003), pyridinoline (= 0.034) and TIMP-1 (= 0.017) determined with the Kruskal–Wallis test. Bars indicate maximum and minimum values within the observation range. values are shown in each panel; N.S. indicates not significant. CRP, C-reactive protein; MMP, matrix metalloproteinase; TIMP, tissue inhibitor of metalloproteinases.


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