Figure S1 - Regulation of Proapoptotic Mammalian ste20–Like Kinase MST2 by the IGF1-Akt Pathway
MST2-induced apoptosis is inhibited by constitutively active Akt. MCF10A cells were transfected with Flag-MST2 and constitutively active HA-myr-Akt. After 36 h of incubation, cells were subjected to Tunel assay (A) and immunoblotting with indicated antibodies (B).
(2.13 MB TIF)