Fig 2.tif (961.45 kB)
Reconstruction of molecular networks that control: (A) “melanogenesis”, (B) “pluripotency of stem cells” and (C) “melanoma”-formation processes.
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posted on 2017-02-03, 18:30 authored by Eumorphia G. Konstantakou, Athanassios D. Velentzas, Athanasios K. Anagnostopoulos, Zoi I. Litou, Ourania A. Konstandi, Aikaterini F. Giannopoulou, Ema Anastasiadou, Gerassimos E. Voutsinas, George Th. Tsangaris, Dimitrios J. StravopodisOrange boxes: WM-266-4 melanoma proteins identified in the present study. Green boxes: proteins that have been missed in this study (for either technical or biological reasons). Red fonts indicate protein products of oncogenes or tumor suppressor genes involved in the disease. The bioinformatics tool engaged was the KEGG pathway maps.
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FGFADT 3 proteinscell-line-derived proteomic collectionEMTdruggable targets Cutaneous melanomaWM -266-4DLLWM -266-4 melanoma proteinsmetastatic melanoma cellsCYTOSCAPEmetastatic melanoma chemotherapeutic refractorinesschromatography-tandem mass spectrometryWM -266-4 cellsKEGGINTACT1433 G family memberBRAFILUNIPROTGAD bioinformatics resourcesaddiction
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