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Q fever antibody ELISA results.

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posted on 2018-10-12, 17:46 authored by Laurie A. Baeten, Brendan K. Podell, Ann E. Sluder, Anja Garritsen, Richard A. Bowen, Mark C. Poznansky

Data are represented as group mean optical density values (OD450) determined using the IDEXX Q fever antibody ELISA. Anti-Coxiella antibody measured in a 1:1,000 dilution of serum collected from guinea pigs at day 0, day 21 (filled shapes) and 42 (open shapes) post-inoculation with C. burnetii Nine Mile. Day 0 antibody levels were similar to saline controls. Data are presented by route of inoculation (intraperitoneal i.p.; intranasal i.n.; saline controls). Error bars represent standard deviations. Group mean OD450 were statistically different from saline controls (one way ANOVA with Tukey’s multiple comparison test; ***P = <0.0001).