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Protein-protein interaction network for the genes selected from the two-stage variable selection algorithm.

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posted on 25.01.2021, 18:50 by Evanthia Koukouli, Dennis Wang, Frank Dondelinger, Juhyun Park

(A) Undirected protein-protein interaction network between the 230 selected (blue) and the BRAF (red) genes (full scale analysis). (B) Undirected protein-protein interaction network between the 65 genes selected from the two-stage variable selection algorithm for the cell lines resistant to BRAF inhibitors (blue) and the BRAF (red) gene. In both panels genes depicted with black are the interaction mediators. Common mediators include the HRAS, MAPK1, MAP2K1 and BAD genes.

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