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Proposed biosynthesis of 6-methylfarnesol in E.coli expressing the GPP-MTase of S. coelicolor.

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posted on 19.04.2018 by Max J. Kschowak, Hannah Wortmann, Jeroen S. Dickschat, Jens Schrader, Markus Buchhaupt

The elongation of 2-MGPP with IPP by an endogenous FPP synthase (FPPS) to 6-methylfarnesyldiphosphate (6-MFPP) and its dephosphorolation by endogenous phosphatases (probably PgpB and YbjG) are assumed.

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