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Pro-inflammatory cytokines expression of IL-1α and IL-1β, and anti-inflammatory cytokine expression of IL-10 in C. albicans treated with lichochalcone-A (62.5 μM and 150 μM), fluconazole (32 μM) (positive control), and 1% ethanol (vehicle control).

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posted on 10.06.2016, 06:59 by Dalia Seleem, Bruna Benso, Juliana Noguti, Vanessa Pardi, Ramiro Mendonça Murata

Significant decrease in IL-1α and IL-1β (*p<0.05), and an increase in IL-10 (results were not statistically significant; p>0.05) in the treated groups compared to the vehicle group. All values are expressed as normalized average expression percentages ± S.e.m (normalized based on the vehicle control groups).