NASH Suppl Material.pdf (107.42 kB)
Preparing for the NASH Epidemic: A Call to Action
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posted on 2021-07-26, 13:48 authored by Fasiha Kanwal, Jay H. Shubrook, Zobair Younossi, Yamini Natarajan, Elisabetta Bugianesi, Mary E. Rinella, Stephen A. Harrison, Christos Mantzoros, Kim Pfotenhauer, Samuel Klein, Robert H. Eckel, Davida Kruger, Hashem El-Serag, Kenneth CusiNonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are common
conditions with a rising burden. Yet, there are significant management gaps between clinical
guidelines and practice in patients with NAFLD and NASH. Further, there is no single global
guiding strategy for the management of NAFLD and NASH. The American Gastroenterological
Association, in collaboration with seven professional associations, convened an international
conference comprising 32 experts in gastroenterology, hepatology, endocrinology, and primary
care providers from the U.S., Europe, Asia, and Australia. Conference content was informed by
the results of a national NASH Needs Assessment Survey. The participants reviewed and
discussed published literature on global burden, screening, risk stratification, diagnosis, and
management of individuals with NAFLD, including those with NASH. Participants identified
promising approaches for clinical practice and prepared a comprehensive, unified strategy for
primary care providers and relevant specialists encompassing the full spectrum of NAFLD/NASH
care. They also identified specific high-yield targets for clinical research and called for a unified,
international public health response to NAFLD and NASH.
conditions with a rising burden. Yet, there are significant management gaps between clinical
guidelines and practice in patients with NAFLD and NASH. Further, there is no single global
guiding strategy for the management of NAFLD and NASH. The American Gastroenterological
Association, in collaboration with seven professional associations, convened an international
conference comprising 32 experts in gastroenterology, hepatology, endocrinology, and primary
care providers from the U.S., Europe, Asia, and Australia. Conference content was informed by
the results of a national NASH Needs Assessment Survey. The participants reviewed and
discussed published literature on global burden, screening, risk stratification, diagnosis, and
management of individuals with NAFLD, including those with NASH. Participants identified
promising approaches for clinical practice and prepared a comprehensive, unified strategy for
primary care providers and relevant specialists encompassing the full spectrum of NAFLD/NASH
care. They also identified specific high-yield targets for clinical research and called for a unified,
international public health response to NAFLD and NASH.
