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Physiologic variables in a representative nonresponder and in a responder acute respiratory distress syndrome (ARDS) patient before, during, and after recruitment maneuvers (RMs)

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posted on 30.12.2011, 22:50 by Enrique Piacentini, Ana Villagrá, Josefina López-Aguilar, Lluis Blanch

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Taken from "Clinical review: The implications of experimental and clinical studies of recruitment maneuvers in acute lung injury"

Critical Care 2003;8(2):115-121.

Published online 5 Sep 2003


Copyright © 2004 BioMed Central Ltd

In patients with a stiff chest wall (nonresponders) the degree of airway pressure transmitted to the pleural space was greater. Subsequently, during the RM, the transpulmonary pressure and the change in lung volume were lower. The reduction in blood pressure was higher in nonresponders than in patients with normal chest wall (responders). From top to bottom: flow, airway opening pressure (Pao), and changes in lung volume (ΔV), esophageal pressure (ΔPes), transpulmonary pressure (P), arterial blood pressure (ABP), and right atrial pressure (RAP) with worsening hemodynamics. Reproduced and modified with permission from Grasso and coworkers [].