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Phenotype of memory OT-I T cells in IFNγ-/- mice, related to Fig 5.

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posted on 2025-03-31, 17:41 authored by Jacob A. Hildebrand, Noah R. Daniels, Emma M. Dehm, Benjamin D. Fisher, Joseph K. Guter, Chris J. Janse, Erin D. Lucas, Jules A. Sangala, Trevor N. Tankersley, Geoffrey T. Hart, Sara E. Hamilton

(A-C) The frequency of OT-I T cells bearing a KLRG1- CD62L- effector memory (Tem), KLRG1- CD62L+ central memory (Tcm), or KLRG1+ CD62L- long-lived effector cell (LLEC) phenotype in the spleen on day 45 p.i. with either ΔActA-Lm-OVA or PbA-OVA in WT (blue and orange) or IFNγ-/- (green and yellow) mice. Data in A-C are pooled from three independent experiments with n = 2-4 mice per group. WT and IFNγ-/- mice were compared using a Mann-Whitney test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. Error bars are SD.

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