Periodicity is characteristic of the chromosome.
(A) Periods of sequential 10 kb fragments from the E. coli K12 MG1655 genome, stepping 5 kb, estimated from the power spectrum of Fourier transformation; data are replotted from Mrázek  Fig 2B, combining data from 0.1 bp intervals to 0.2 bp intervals. Fragments within 0.6 bp of the genomic period (11.05 bp) are shaded black. (B) Distribution of periods for best-fit curves of the autocorrelations of dinucleotide spacings of 270,000 random 10 kb fragments of the E. coli K12 MG1655 genome. Fragments within 0.6 bp of the genomic period (11.05 bp) are shaded black, fragments with periods estimated in the lower (5.0–6.0 bp) and higher (17.0–18.0 bp) ranges are shown in red and blue, respectively. The insets show percentages of estimated periods for sequences generated by pooling 2, 3, or 5 fragments initially showing periods within the lower (left inset) or higher (right inset) range of explored periods. Bars in the insets are color-coded to the ranges denoted in the primary figure.
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