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Download filePRN contributed to the generation of anti-B. bronchiseptica IgG antibodies.
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posted on 2021-08-04, 17:35 authored by Longhuan Ma, Kalyan K. Dewan, Dawn L. Taylor-Mulneix, Shannon M. Wagner, Bodo Linz, Israel Rivera, Yang Su, Amanda D. Caulfield, Uriel Blas-Machado, Eric T. HarvillIgG antibody titers against B. bronchiseptica were determined in sera of C3H/HeJ mice infected with either Bb WT (blue) or BbΔprn (orange) at 28 dpi. There were 4 mice per group. Error bars show the standard error of mean. Statistical significance was calculated by using One-way ANOVA. *p < 0.05, **p < 0.01, ***p < 0.001.
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neutrophil-mediated clearancePrevious studiesPRNimmunomodulatory factormucus accumulationBordetella pertussisvaccine antigenUnited StateshostWT strainpertactin-deficient bacteriavaccine-driven evolutionvaccine coverageaugments inflammationpertactin-deficient strainTNF -αC 3H micedose inoculationmucus productionbronchiseptica pertactin deletionBordetella bronchiseptica Whooping ...novel strategiesmurine macrophagesintracellular survivalHistological examinationWT B
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