Mv-v14-1020-f5.jpg (26.37 kB)

PDGF-induced cell migration involves JAK2-STAT3 pathway

figure

posted on 2011-12-30, 21:18 authored by Neeraj Vij, Ajay Sharma, Mahesh Thakkar, Sunilima Sinha, Rajiv R. Mohan

Human corneal fibroblasts were exposed to PDGF in the presence or absence of JAK2-STAT3 inhibitor, AG-490, for 8 h, and cell migration was quantified using the Boyden chamber chemotaxis assay. PDGF-induced corneal fibroblast migration was inhibited significatly by AG-490. The asterisk indicates a p

Copyright information:

Taken from "PDGF-driven proliferation, migration, and IL8 chemokine secretion in human corneal fibroblasts involve JAK2-STAT3 signaling pathway"

Molecular Vision 2008;14():1020-1027.

Published online 30 May 2008

PMCID:PMC2408775.