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PDGF-induced cell migration involves JAK2-STAT3 pathway

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posted on 2011-12-30, 21:18 authored by Neeraj Vij, Ajay Sharma, Mahesh Thakkar, Sunilima Sinha, Rajiv R. Mohan
Human corneal fibroblasts were exposed to PDGF in the presence or absence of JAK2-STAT3 inhibitor, AG-490, for 8 h, and cell migration was quantified using the Boyden chamber chemotaxis assay. PDGF-induced corneal fibroblast migration was inhibited significatly by AG-490. The asterisk indicates a p

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Taken from "PDGF-driven proliferation, migration, and IL8 chemokine secretion in human corneal fibroblasts involve JAK2-STAT3 signaling pathway"

Molecular Vision 2008;14():1020-1027.

Published online 30 May 2008

PMCID:PMC2408775.

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