pone.0202201.g001.tif (2.74 MB)
Download fileNigrostriatal track volume.
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posted on 2018-09-05, 17:30 authored by Joshua S. Shimony, Jerrel Rutlin, Morvarid Karimi, Linlin Tian, Abraham Z. Snyder, Susan K. Loftin, Scott A. Norris, Joel S. PerlmutterT2 weighted coronal image through the striatum (A) and FA weighted image (B) with superposed nigrostriatal track volumes (right in orange and left in blue) in a single monkey. Analogous transverse images at a level above the substantia nigra are shown in (C) and (D).
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Keywords
video-based motor ratingsNHPConclusion Diffusion measuresMRIstriatal dopamine concentrationvivo PET measuresstriatal PET measuresstriatal fiber densitymacaques Objective Interpretationnigral cell countsnigral TH cell count lossnigrostriatal tractnigral dopamine neuronsnigrostriatal injuryimmunostained fiber densitystriatal TH-positive fiber densityResults Diffusion measuresdiffusion tensor imaging measurescarotid artery infusionstereologic terminal field measuresterminal field measuresMPTPnigrostriatal terminal field measuresstriatal tyrosine hydroxylasenigral TH-positive cell bodiesdiffusion measures
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