Network of the studies used in the meta-analysis.
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posted on 2017-11-14, 18:39 authored by Julian F. Guest, Jaime Esteban, Anton G. Manganelli, Andrea Novelli, Giuliano Rizzardini, Miquel SerraAbbreviations: DAL: dalbavancin; DAP: daptomycin; LZD: linezolid; TEI: teicoplanin; VAN: vancomycin; TIG: tigecycline. *Includes studies where the comparator was vancomycin, vancomycin plus aztreonam. Or vancomycin plus conventional treatment. Each node represents a treatment and the connecting lines indicate pairs of treatments that have been directly compared in one RCT. The numbers in the connecting lines indicate the number of relevant studies for each treatment comparison.
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Comparative efficacySAETOC visitorganisational settingspatient managementMethods Comparatorsdalbavancinnetwork meta-analysis Objectivelikelihoodpatient subgroupConclusion DalbavancinResults Study interventionsrandom-effect modelSafety-related endpointsalternative IV antimicrobial agentNMAskin structure infectionstreatment successABSSSI patientsEfficacy-related endpointsAEdiscontinuation ratelinezolidrandomised control trialshealthcare systemscomparatorall-cause mortalityIV antibiotics
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