Positions of the MSM mutations in the slow/β-cardiac MyHC rod domain.
Figures are generally photos, graphs and static images that would be represented in traditional pdf publications.
The globular head domain is shown in red. (A) The neck domain is shown in yellow and the C-terminal LMM segment of the rod domain is shown in orange. The heptad repeat motif forms the structural basis for coiled-coil dimer of the β-MyHC. (B) The positions of slow/β-cardiac MyHC mutations associated with MSM in the heptad repeat motif are indicated. (C) Differentiated human myotubes stained with MyHC show clear A-bands (white bracket).