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Multivariable adjusted risk of any infection for individuals from the Copenhagen General Population Study with lymphopenia (lymphocyte count < 1.1 × 109/l) compared to individuals with lymphocytes in the reference range (1.1–3.7 × 109/l).

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posted on 2018-11-01, 17:36 authored by Marie Warny, Jens Helby, Børge Grønne Nordestgaard, Henrik Birgens, Stig Egil Bojesen

Multivariable adjustment includes all covariates listed in Table 1 except age, but with age as the underlying timescale. The sum number of individuals in the strata varies slightly because of varying numbers of individuals with missing data in the covariates. When categorizing lymphocyte counts, lymphopenia was defined as a lymphocyte count below the 2.5th percentile, while the reference category was defined as a lymphocyte count between the 2.5th and 97.5th percentile. NSNot significant after adjusting for 12 multiple comparisons using the Bonferroni method.aAccording to a likelihood ratio test.b≤168 versus >168 g/week for men and ≤84 versus >84 g/week for women.cWhen categorizing neutrophil counts, neutropenia was defined as a neutrophil count below 1.5 × 109/l, which is the generally accepted lower cutoff [4,4143], the reference category was defined as a neutrophil count from 1.5 × 109/l to 5.9 × 109/l, and neutrocytosis was defined as a neutrophil count above 5.9 × 109/l.dAs defined by the Charlson comorbidity index.

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