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Morphology of human neutrophils after prolonged QVD treatment.

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posted on 2025-01-07, 18:27 authored by Lisa Khuu, Alisha Pillay, Allan Prichard, Lee-Ann H. Allen

Representative Hema-3 images of human neutrophils that were incubated in medium containing 10 μM QVD for 6–10 days (Q6-Q10) and then stained with Hema-3 reagents. Arrows indicate cytoplasmic vacuoles.

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    PLOS ONE

    Categories

    • Biochemistry
    • Cell Biology
    • Genetics
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    Keywords

    somewhat different extentsregarding functional capacityphosphatidylserine externalization togetherleast 5 dayshost defense functionscertain growth factorshuman neutrophil viabilityhuman neutrophil lifespannadph oxidase activitydiv >< pmolecular level apoptosisconstitutive apoptosis programcaspase inhibitor q11 maintained following qoph prevented agefunction caspase activityvitro human neutrophilsexecutioner caspasedelay apoptosisnuclear morphologylived leukocyteslarge bodyinflammatory mediatorsinfectious agentsinduce neutrophilsglutathione levelsfunction coulddna fragmentationday viadata demonstratesdata demonstratecurrent studycell isolationapproximately 101 ).

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