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Modular decomposition of the DynamoYeast model via null space analysis.

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posted on 2021-07-15, 17:44 authored by Marianyela Sabina Petrizzelli, Dominique de Vienne, Thibault Nidelet, Camille Noûs, Christine Dillmann

The null space of the stoichiometric matrix of the DynamoYeast model is spanned by the columns of the 70 reactions × 16 null-space matrix. Hierarchical clustering is applied using as a metric the angles between the 16 dimensional row vectors reactions. The reactions associated with enzymatic proteins quantified in this study are in blue, the other reactions present in the DynamoYeast model are in black.