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Model variation including CA3c backprojections compared with the current model The figure on the left A) shows the CA3 in the current version of the educational model.

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posted on 2025-04-29, 18:13 authored by Lucas Longo, Thiago Lima, Maria Clara Bila, João Brogin, Jean Faber

The neurons arranged into recurrent excitation motifs (green) are responsible for the high firing frequency measured by the voltmeters. Whereas the other figure B) shows a model variant including the CA3c backprojection to DG. An intense inhibition, mainly caused by a sequence of delayed feedback inhibition motifs (in orange) produce a bursting pattern in CA3c cells as shown by the voltmerer. Those cells project back to DG, stimulating two inhibitory and one excitatory cell.

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