pone.0224743.g004.tif (2.16 MB)
Download fileMedian-joining networks of Plasmodium knowlesi MSP4 nucleotide haplotypes from Malaysia.
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posted on 2019-11-21, 19:07 authored by Md Atique Ahmed, Ahmed Saif, Fu-Shi QuanThe genealogical haplotype network shows the relationships among the 24 haplotypes present in the 36 nucleotide sequences obtained from clinical isolates of Sarawak, Malaysian Borneo and laboratory adapted strains. Each distinct haplotype has been designated a number (H_n). Circle sizes represent the frequencies of the corresponding haplotype (the number is indicated for those that were observed >1×). Distances between nodes are arbitrary. The small red circles are median vectors (marked mv1) randomly generated by the software while constructing the network.
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EGFpopulation structurePeninsular Malaysia2 non-synonymous substitutionsHigh population differentiation values4 lab-adapted strainsexon IIPlasmodium knowlesi merozoite surface protein 4Malaysia Human infectionsvaccinemsp 4 geneterminal epidermal growth factorMalaysian BorneoMSPsamplePhylogenetic haplotype network analysispolymorphismmonkey malaria parasite Plasmodium knowlesi