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MOESM1 of Infections with Plasmodium falciparum during pregnancy affect VAR2CSA DBL-5 domain-specific T cell cytokine responses

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posted on 21.09.2016, 05:00 by Komi Gbédandé, Gilles Cottrell, Bertin Vianou, Samad Ibitokou, Aurax Fernando, Marita Troye-Blomberg, Ali Salanti, Kabirou Moutairou, Achille Massougbodji, Nicaise Ndam, Philippe Deloron, Adrian Luty, Nadine Fievet
Additional file 1. Cytokines profile in response to PHA and to DBL-5 stimulation of PBMC at inclusion and at delivery. The frequencies of IFN-γ-secreting T cells and cytokine production in PBMC at delivery in response to PHA or to the recombinant protein DBL-5 are shown. Except for IFN-γ and IL-13 production in response to DBL-5, all box plots illustrate medians with 25th and 75th percentiles and whiskers for 10th and 90th percentiles. The box plots for IFN-γ and IL-13 production in response to DBL-5 indicate the mean with SEM (standard error of the mean). The univariate statistical significance of differences between groups was determined using the nonparametric Mann–Whitney U test, p < 0.05.


Seventh Framework Programme